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As you go through menopause, you may grapple with hot flashes, mood swings, and sleep disturbances, all symptoms of fluctuating estrogen and progesterone levels in your body. You yearn for relief, for that elusive sense of balance and vitality you once had. Hormone therapy is one of the most effective ways to combat the symptoms of menopause, allowing you to regain the balance and vitality that makes you feel youthful again.

However, you have one significant choice to make: do you use natural or synthetic hormones? At Fountain of You MD, we understand the importance of making informed choices about your health. We offer a wide range of hormone therapies for women undergoing menopause, including progesterone medication, testosterone and estradiol creams, and BioTE bioidentical hormone replacement therapy using hormone pellets. In this article, we’ll explore the differences between natural and synthetic hormones.


Natural (bioidentical) hormones have the same chemical structure as hormones produced in the body. These hormones are derived from plant sources, such as yams or soybeans, and mimic the body’s own hormones, including estrogen, progesterone, and testosterone. Because they are structurally identical to the body’s hormones, natural hormones are better tolerated and more easily metabolized compared to synthetic counterparts.

Synthetic hormones, on the other hand, are created in a laboratory and have a similar but not identical structure to natural hormones. While synthetic hormones can effectively alleviate menopause symptoms, they may also pose greater risks of side effects and adverse reactions due to their non-identical structure and potential interactions with the body’s receptors.


Both natural and synthetic hormones can provide relief from menopause symptoms. However, studies suggest that natural hormones may offer advantages in terms of symptom management and overall well-being. Bioidentical hormone replacement therapy (BHRT), which utilizes natural hormones, has been shown to effectively alleviate hot flashes, night sweats, vaginal dryness, and mood swings in many women. Additionally, BHRT may offer a more individualized approach to hormone therapy, allowing for customized dosing based on each patient’s unique needs.

Safety Profile

Natural hormones are often believed to be safer alternatives to synthetic hormones due to their identical chemical structure and more natural processing within the body. Since they resemble the hormones produced by the body, there’s a lower risk of adverse reactions. However, even synthetic hormone therapies are perfectly safe when administered by skilled providers in controlled doses. While all hormone therapies carry risks like hormone imbalances, the risks are often managed through continuous monitoring and adjustment.

Administration Method

Synthetic hormones are commonly available in various forms, including pills, patches, creams, and injections. In contrast, bioidentical hormones are often prescribed in customized formulations tailored to each patient’s needs. At Fountain of You MD, we offer BioTE bioidentical hormone replacement therapy using hormone pellets, which are implanted under the skin and gradually release hormones into the body over time. This provides a convenient and consistent delivery of hormones, minimizing fluctuations and optimizing therapeutic effects.

Choosing between natural and synthetic hormones for menopause treatment is a personal decision that should be made based on careful consideration. At Fountain of You MD, we strive to empower women with the knowledge and resources they need to make informed choices about their health. Our team is happy to discuss your options and recommend the most appropriate hormone replacement options for your specific needs to help you reclaim vitality. Contact us today!

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